BDBM50098414 CHEMBL3593247

SMILES CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(CNC(=O)C[C@H](OC1=O)\C=C\CCS)n2

InChI Key InChIKey=VEDPEVJAYWVUSJ-BNVDZZMOSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098414   

TargetHistone deacetylase 6(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  42nMAssay Description:Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 after 30 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098414(CHEMBL3593247)
Affinity DataIC50:  121nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed